B3

৳ 300

Indication: B3 Tablet is indicated for the prevention and treatment of deficiency of vitamin B1, B6, B12 and as prophylaxis of:

  • Diabetic
  • neuropathy
  • Peripheral neuralgia
  • Lumbago
  • Myalgia
  • Optic Neuritis
  • Sciatica
  • Facial neuralgia
  • Intercostal neuralgia
  • Spinal pain
  • Beri-beri, debility, pyridoxine responsive anemia

Composition:

Each film-coated tablet contains Thiamine Mononitrate USP (Vitamin B1) 100 mg, Pyridoxine Hydrochloride BP (Vitamin B6) 200 mg, Cyanocobalamin BP (Vitamin B12) 200 mcg.

Therapeutic Class: Vitamin & Minerals

Generic Name: Vitamin BI USP, Vitamin B6 BP. & Vitamin B12 BP

Trade Name:

Category: Tag:

Description

Pharmacology: Vitamin B1 (Thiamine) forms thiamine pyrophosphate by combining with adenosine triphosphate; essential coenzyme in carbohydrate metabolism. Vitamin B6 (Pyridoxine) is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. Vitamin B12 (cobalamin) is a water-soluble vitamin that has a key role in the normal functioning of the brain and nervous system, and the formation of red blood cells. It is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis, fatty acid and amino acid metabolism. Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin) play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body’s own repair mechanism and work in pain management.

 Dose & Administration: Tablets may be administered in a dose of 1 to 3 tablets per day or as directed by the physician.

Contraindications: Should not be used in the patients on Levodopa therapy and hypersensitivity to any of the active ingredients.

Warning and Precautions: Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of spinal cord. Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.

Side Effects:

a) Common: Generally well tolerated.

b) Rare: A few allergic reactions may be seen.

Use in Pregnancy & Lactation: B3 Tablet is safe for the pregnant women and may be used in pregnancy. It is not known whether thiamine (Vitamin B1) is excreted in breast milk or not but may take in cautiously during lactation. Thiamine excretes into breast milk. Vitamin-B6 and Vitamin-B12 have no adverse effect or side during lactation.

Use in children & adolescents: B3 may give to children who are able to swallow the tablet as a whole.

Drug Interaction:

a) With Medicine: Pyridoxine (vitamin-B6) reduces therapeutic effect of levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, chloramphenicol, aminosalicylic acid and H-2 receptor antagonist may reduce Vitamin B12 adsorption.

b) With Food and others: Alcohol prevents body from absorbing some nutrients, and increases risk of a vitamin B-12 deficiency. Dairy products of food with high calcium content should be avoided with this tablet.

Overdose: There is no known overdose.

Storage: B3 Tablet: Store below 30° C, protected from light and moisture. Keep away from the reach of the children. Packing: B3 Tablet: Each box contains 5×10’s tablets in blister pack.

Additional information

Piece

50 Tablets

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