Indication: Skin and nail infections due to dermatophytes, yeasts and other fungi such as: Tinea capitis, corporis, manuum, pedis, barbae, cruris, unguium or onychomycosis. Pityriasis versicolor, candidiasis of skin and nails, stomatitis angularis, otitis externa. Since Miconazole Nitrate has an antibacterial effect on Gram-positive bacteria, it may be used in mycoses secondarily infected with such bacteria
Composition : Each gram of Miaz topical cream contains Miconazole Nitrate BP 20 mg.
Therapeutic Class: Topical Preparation
Generic Name: Miconazole Nitrate BP
Pharmacology: Miconazole Nitrate is a broad-spectrum antimycotic which offers a high antifungal activity against dermatophytes, yeasts and other phyco-Asco and Adelomycetes, with a potent antibacterial activity against Gram-positive bacilli and cocci. Miconazole Nitrate proved to be markedly effective in secondary infected mycoses, which under other treatments were resistant or reappeared. Miconazole Nitrate does not stain skin or clothes.
Dosage and administration: The dosage is same for all the ages. For skin infections: Apply some cream to the lesions twice daily and rub it well with finger until it has fully penetrated the skin. All lesions usually disappear after 2 to 5 weeks. Prolong treatment for some 10 days to prevent relapse. For nail infections: Clip infected nail as shortly as possible. Apply some cream once daily to the infected nail and rub with your finger, cover nail with a non-perforated occlusive plastic bandage. Also after loosening of the infected nail (from 2-3 weeks onwards) uninterrupted treatment should be continued until the growth of a new nail has set in and definite cure can be observed (usually after seven months or more).
Contraindication: It should not use with sensitive to Miconazole or any of the ingredients. It should not use with similar antifungal agents such as ketoconazole.
Warning & Precaution: It should be used with caution when applied to extensive surface areas or under occlusive dressings including baby napkins. Application to extensive to surface areas of the face should be avoided. In infants long term continuous therapy should be avoided. The infected area should be kept clean and dry during treatment. Side effect:
a) Common: Burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin may occur.
b) Rare: A very serious allergic reaction including: rash, itching/swelling, severe dizziness, trouble breathing.
Use in pregnancy and lactation: Only small amounts of Miconazole nitrate are absorbed following local administration. However Miconazole nitrate should be used with caution during pregnancy.
Drug interaction: Amphotericin antagonizes effect of Miconazole.
Overdosage: Miconazole Nitrate is intended for topical use. If accidental ingestion of large quantities of the product occurs, an appropriate method of gastric emptying may be used if considered desirable.
Storage: Store below 30°c, protected from light & moisture.
Keep away from the reach of the children.
Packaging: Miaz: Each tube containing 10 gm cream.