B3

৳ 300

Brand Name: B3
Generic Name: Vitamin BI USP, Vitamin B6 BP. & Vitamin B12 BP
Therapeutic Class: Vitamin & Minerals

View Prescribing Details

Additional information

STRENGTH	50 Tablets

Presentation

Each film-coated tablet contains Thiamine Mononitrate USP (Vitamin B1) 100 mg, Pyridoxine Hydrochloride BP (Vitamin B6) 200 mg, Cyanocobalamin BP (Vitamin B12) 200 mcg.

Description

Vitamin B1 (Thiamine) forms thiamine pyrophosphate by combining with adenosine triphosphate; essential coenzyme in carbohydrate metabolism. Vitamin B6 (Pyridoxine) is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. Vitamin B12 (cobalamin) is a water-soluble vitamin that has a key role in the normal functioning of the brain and nervous system, and the formation of red blood cells. It is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis, fatty acid and amino acid metabolism. Vitamin B1 (Thiamine), B6 (Pyridoxine) & B12 (Cyanocobalamin) play essential role as co-enzyme for the metabolism of nervous system. Thus this combination normalizes the nerve cell metabolism. This combination supports the regeneration of nerve fibers and myelin sheath by activation of the metabolism and the natural repair mechanism. The combination of these 3 vitamins shows better efficacy than that of the individual components. In addition, Vitamin B1, B6 & B12 promote body’s own repair mechanism and work in pain management.

Indication

B3 Tablet is indicated for the prevention and treatment of deficiency of vitamin B1, B6, B12 and as prophylaxis of:

Diabetic
neuropathy
Peripheral neuralgia
Lumbago
Myalgia
Optic Neuritis
Sciatica
Facial neuralgia
Intercostal neuralgia
Spinal pain
Beri-beri, debility, pyridoxine responsive anemia

Dose And Administration

Tablets may be administered in a dose of 1 to 3 tablets per day or as directed by the physician.

Side Effect

a) Common: Generally well tolerated.

b) Rare: A few allergic reactions may be seen.

Warning & Precaution

Cyanocobalamin should not be given before a diagnosis has been fully established because of the possibility of masking symptoms of subacute degeneration of spinal cord. Cyanocobalamin is not a suitable form of Vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.

Contraindication

Should not be used in the patients on Levodopa therapy and hypersensitivity to any of the active ingredients.

Use In Pregnancy And Lactation

B3 Tablet is safe for the pregnant women and may be used in pregnancy. It is not known whether thiamine (Vitamin B1) is excreted in breast milk or not but may take in cautiously during lactation. Thiamine excretes into breast milk. Vitamin-B6 and Vitamin-B12 have no adverse effect or side during lactation.

Packaging

B3 Tablet: Each box contains 5×10’s tablets in blister pack.

Drug Interaction

a) With Medicine: Pyridoxine (vitamin-B6) reduces therapeutic effect of levodopa but it does not occur if a dopa decarboxylase inhibitor is also given. Neomycin, chloramphenicol, aminosalicylic acid and H-2 receptor antagonist may reduce Vitamin B12 adsorption.

b) With Food and others: Alcohol prevents body from absorbing some nutrients, and increases risk of a vitamin B-12 deficiency. Dairy products of food with high calcium content should be avoided with this tablet.